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Current Challenges and Implications of Proteogenomic Approaches in Prostate Cancer.
Current Topics in Medicinal Chemistry ( IF 2.9 ) Pub Date : 2020-08-31 , DOI: 10.2174/1568026620666200722112450 Nidhi Shukla 1, 2 , Narmadhaa Siva 1 , Babita Malik 2 , Prashanth Suravajhala 1
中文翻译：
蛋白质组学方法在前列腺癌中的当前挑战和启示。
更新日期：2020-10-08
Current Topics in Medicinal Chemistry ( IF 2.9 ) Pub Date : 2020-08-31 , DOI: 10.2174/1568026620666200722112450 Nidhi Shukla 1, 2 , Narmadhaa Siva 1 , Babita Malik 2 , Prashanth Suravajhala 1
Affiliation
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In the recent past, next-generation sequencing (NGS) approaches have heralded the omics era. With NGS data burgeoning, there arose a need to disseminate the omic data better. Proteogenomics has been vividly used for characterising the functions of candidate genes and is applied in ascertaining various diseased phenotypes, including cancers. However, not much is known about the role and application of proteogenomics, especially Prostate Cancer (PCa). In this review, we outline the need for proteogenomic approaches, their applications and their role in PCa.
中文翻译：
蛋白质组学方法在前列腺癌中的当前挑战和启示。
在最近的过去，下一代测序（NGS）方法预示了组学时代。随着NGS数据的蓬勃发展，需要更好地传播Omic数据。蛋白质组学已被生动地用于表征候选基因的功能，并被用于确定各种疾病的表型，包括癌症。但是，关于蛋白质组学，尤其是前列腺癌（PCa）的作用和应用还知之甚少。在这篇综述中，我们概述了蛋白质组学方法的需求，其应用及其在PCa中的作用。
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