Food-associated outbreaks linked to enteropathogenic Yersinia enterocolitica are of concern to public health. Pigs and their meat are recognized risk factors for transmission of Y. enterocolitica . This study aimed to describe the comparative genomics of Y. enterocolitica along with a number of misclassified Yersinia isolates, now constituting the recently described Yersinia hibernica . The latter was originally cultured from an environmental sample taken at a pig slaughterhouse. Unique features were identified in the genome of Y. hibernica, including a novel integrative conjugative element (ICE), denoted as ICE Yh-1 contained within a 255 kbp region of plasticity. In addition, a zebrafish embryo infection model was adapted and applied to assess the virulence potential among Yersinia isolates including Y. hibernica .

中文翻译：

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对冬眠耶尔森菌的比较基因组见解 - 一种经常被错误识别的类似小肠结肠炎耶尔森菌的生物体。


与肠道病原性小肠结肠炎耶尔森菌有关的食品相关疫情引起了公众健康的关注。猪及其肉类被认为是传播小肠结肠炎耶尔森氏菌的危险因素。本研究旨在描述小肠结肠炎耶尔森氏菌以及一些错误分类的耶尔森氏菌分离株的比较基因组学，这些菌株现在构成了最近描述的冬眠耶尔森氏菌。后者最初是从生猪屠宰场采集的环境样本中培养出来的。在Y. hibernica 基因组中发现了独特的特征，包括一种新的整合接合元件 (ICE)，表示为 ICE Yh-1 ，包含在 255 kbp 的可塑性区域中。此外，还采用斑马鱼胚胎感染模型来评估包括冬眠耶尔森氏菌在内的耶尔森氏菌分离株的毒力潜力。