Necroptosis is a cell death pathway involved in inflammation and disease. In this issue, Ko et al. (2020. J. Cell Biol.https://doi.org/10.1083/jcb.201912047) link SARM1, the executioner of Wallerian degeneration of axons, to necroptosis, revealing a unique form of axonal disassembly likely involved in neurodegenerative disorders.

中文翻译：

---

坏死性凋亡对您的健康有益


坏死性凋亡是一种与炎症和疾病有关的细胞死亡途径。在本期中，Ko 等人。 (2020. J. Cell Biol.https://doi.org/10.1083/jcb.201912047) 将轴突沃勒变性的执行者 SARM1 与坏死性凋亡联系起来，揭示了可能与神经退行性疾病有关的一种独特的轴突分解形式。