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Streptomyces from traditional medicine: sources of new innovations in antibiotic discovery.
Journal of Medical Microbiology ( IF 2.4 ) Pub Date : 2020-08-01 , DOI: 10.1099/jmm.0.001232
Gerry A Quinn 1 , Aiya M Banat 2 , Alyaa M Abdelhameed 3 , Ibrahim M Banat 1
Affiliation  

Given the increased reporting of multi-resistant bacteria and the shortage of newly approved medicines, researchers have been looking towards extreme and unusual environments as a new source of antibiotics. Streptomyces currently provides many of the world’s clinical antibiotics, so it comes as no surprise that these bacteria have recently been isolated from traditional medicine. Given the wide array of traditional medicines, it is hoped that these discoveries can provide the much sought after core structure diversity that will be required of a new generation of antibiotics. This review discusses the contribution of Streptomyces to antibiotics and the potential of newly discovered species in traditional medicine. We also explore how knowledge of traditional medicines can aid current initiatives in sourcing new and chemically diverse antibiotics.

中文翻译:


传统医学中的链霉菌:抗生素发现新创新的来源。



鉴于多重耐药细菌的报道增多以及新批准药物的短缺,研究人员一直在寻找极端和不寻常的环境作为抗生素的新来源。链霉菌目前提供了世界上许多临床抗生素,因此这些细菌最近从传统药物中分离出来也就不足为奇了。鉴于传统药物种类繁多,希望这些发现能够提供新一代抗生素所需的备受追捧的核心结构多样性。这篇综述讨论了链霉菌对抗生素的贡献以及新发现的物种在传统医学中的潜力。我们还探讨了传统医学知识如何帮助当前采购新型和化学多样性抗生素的举措。
更新日期:2020-08-27
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