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The Ingenuity of Bacterial Genomes.
Annual Review of Microbiology ( IF 8.5 ) Pub Date : 2020-09-09 , DOI: 10.1146/annurev-micro-020518-115822
Paul C Kirchberger 1 , Marian L Schmidt 1 , Howard Ochman 1
Affiliation  

The genomes of bacteria contain fewer genes and substantially less noncoding DNA than those of eukaryotes, and as a result, they have much less raw material to invent new traits. Yet, bacteria are vastly more taxonomically diverse, numerically abundant, and globally successful in colonizing new habitats compared to eukaryotes. Although bacterial genomes are generally considered to be optimized for efficient growth and rapid adaptation, nonadaptive processes have played a major role in shaping the size, contents, and compact organization of bacterial genomes and have allowed the establishment of deleterious traits that serve as the raw materials for genetic innovation.

中文翻译:


细菌基因组的独创性。

与真核生物相比,细菌的基因组包含更少的基因和更少的非编码 DNA,因此,它们用于发明新特性的原材料要少得多。然而,与真核生物相比,细菌在分类学上更加多样化,数量上更加丰富,并且在全球范围内成功地殖民新的栖息地。尽管通常认为细菌基因组经过优化以实现高效生长和快速适应,但非适应性过程在塑造细菌基因组的大小、内容和紧凑组织方面发挥了重要作用,并允许建立用作原材料的有害性状用于基因创新。

更新日期:2020-09-10
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