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Investigation of dynamic deformation of the midbrain in rear-end collision using human brain FE model
Computer Methods in Biomechanics and Biomedical Engineering ( IF 1.7 ) Pub Date : 2020-07-20 , DOI: 10.1080/10255842.2020.1795142
Noritoshi Atsumi 1 , Masami Iwamoto 1 , Yuko Nakahira 1 , Yoshitaka Asano 2, 3 , Jun Shinoda 2, 3
Affiliation  

Abstract Mild traumatic brain injury (TBI), including concussions, can cause symptoms affecting physical or cognitive domains in the acute and chronic phases. In this study, we investigated the dynamic deformation of the brain stem, which might be important for these symptoms, using a human brain finite element model through reconstruction simulations of rear-end collisions in three different velocities. In all simulations, high maximum principal strain values were observed at the midbrain that were higher than those in the corpus callosum. These findings could provide some mechanical insights into brain disorders associated with mild TBI.

中文翻译:

基于人脑有限元模型的追尾碰撞中脑动态变形研究

摘要 轻度创伤性脑损伤 (TBI),包括脑震荡,可在急性和慢性阶段引起影响身体或认知领域的症状。在这项研究中,我们使用人脑有限元模型,通过三种不同速度下追尾碰撞的重建模拟,研究了脑干的动态变形,这可能对这些症状很重要。在所有模拟中,在中脑观察到的最大主应变值高于胼胝体。这些发现可以为与轻度 TBI 相关的脑部疾病提供一些机械见解。
更新日期:2020-07-20
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