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An Insight into Unani Hypoglycemic Drugs and Their Mechanism of Action
Combinatorial Chemistry & High Throughput Screening ( IF 1.6 ) Pub Date : 2021-01-31 , DOI: 10.2174/1386207323666200717143540
Mohammad Fazil 1 , Sadia Nikhat 2 , Imran Ali 3
Affiliation  

Background: Diabetes mellitus type-II is a major health problem characterized by hypoinsulinemia and insulin resistance, leading to hyperglycemia and its complications. In Unani medicine, it is known as ziyābetus. Several drugs are prescribed in Unani medicine as single and compound formulations for this disease. Most of these drugs have been studied on scientific parameters and shown significant activity in reducing the symptoms and complications of diabetes.

Objectives: Critical evaluation of Unani medicines for treating diabetes patients have been conducted. The aim of the study is to provide complete information on this subject with the action of the mechanism so that proper treatment should be done with prospective research.

Methods: Unani literature was reviewed extensively via various search engines for the herbs, shrubs used for diabetes treatment. Ten drugs were selected for the present review.

Results and Conclusion: There is convincing evidence to suggest that the selected drugs have promising actions against diabetes and its complications. In addition, none of the studies has reported any adverse effects with the drugs. Also, there is evidence to suggest that the method of usage described in Unani medicine may reduce or eliminate adverse events, if any. Further, there is a great need to do more research on making medicine more effective. Besides, the review article is useful for treating patients effectively by advancing the research.



中文翻译:

深入了解 Unani 降血糖药物及其作用机制

背景:II 型糖尿病是一种以低胰岛素血症和胰岛素抵抗为特征的主要健康问题,可导致高血糖及其并发症。在 Unani 医学中,它被称为 ziyābetus。Unani 药物中规定了几种药物作为该疾病的单一和复合制剂。大多数这些药物已经根据科学参数进行了研究,并且在减少糖尿病的症状和并发症方面显示出显着的活性。

目标:对用于治疗糖尿病患者的 Unani 药物进行了严格评估。该研究的目的是通过机制的作用提供有关该主题的完整信息,以便通过前瞻性研究进行适当的治疗。

方法:通过各种搜索引擎对用于治疗糖尿病的草药、灌木进行了广泛的 Unani 文献审查。本次审查选择了 10 种药物。

结果和结论:有令人信服的证据表明所选药物对糖尿病及其并发症具有良好的疗效。此外,没有一项研究报告了这些药物的任何不良反应。此外,有证据表明 Unani 药物中描述的使用方法可以减少或消除不良事件(如果有)。此外,非常需要做更多关于使药物更有效的研究。此外,该评论文章有助于通过推进研究来有效治疗患者。

更新日期:2021-02-11
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