Consecutive substitution reactions of arsenic(III)chloride with sodium salts of various oximes and morpholinedithiocarbamate (morphdtc) were carried out in 1:2:1 stoichiometry to obtain six new arsenic(III) mixed derivatives of the type: [(R)(R¹)C = NO]₂Sb[S₂CN(CH₂CH₂)₂O] [where R is –C₆H₅, R¹ = –CH₃ (1); R = –C₆H₄CH₃, R¹ = –CH₃ (2); R = –C₆H₄Cl, R¹ = –CH₃ (3); R = –C₆H₄Br, R¹ = –CH₃ (4); R = –C₆H₄OH, R¹ = –H (5); R(R¹)C = (6)]. These derivatives are characterized by elemental and physicochemical analyses and the tentative distorted trigonalbipyramidal geometry around arsenic assigned using spectral data of infrared (¹H, ¹³C) nuclear magnetic resonance and liquid chromatography‐mass. Powder X‐ray diffraction study revealed their nanoranged particle size to be approximately 40 nm and crystalline nature. These derivatives examined against microbes and results revealed that these derivatives expressed more antifungal potential than antibacterial. The antioxidant activity was carried out by ferric reducing ability of plasma assay, and the cytotoxic study was performed in 3T₃ fibroblast cell lines by tetrazolium‐based colorimetric assay.

中文翻译：

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具有肟和吗啉代二硫代氨基甲酸酯的砷（III）混合衍生物，以及它们的细胞毒性，抗菌和抗氧化剂研究。

以化学计量比为1：2：1的方式连续进行氯化砷（III）与各种肟的钠盐和吗啉二硫代氨基甲酸酯（morphdtc）的取代反应，从而得到六种新的类型的砷（III）混合衍生物：¹）C = NO] ₂ Sb [S ₂ CN（CH ₂ CH ₂）₂ O] [其中R为–C ₆ H ₅，R ¹  = –CH ₃（1）；R = –C ₆ H ₄ CH ₃，R ¹  = –CH ₃（2）；R = –C ₆ H ₄ Cl，R¹  = –CH ₃（3）; R = –C ₆ H ₄ Br，R ¹  = –CH ₃（4）；R = –C ₆ H ₄ OH，R ¹  = –H（5）；R（R ¹）C ＝（6）]。这些衍生物的特征在于元素和物理化学分析，以及使用红外光谱数据（¹ H，¹³C）核磁共振和液相色谱-质谱。粉末X射线衍射研究表明，它们的纳米级粒径约为40 nm，具有晶体性质。这些衍生物针对微生物进行了检测，结果表明，这些衍生物比抗菌剂具有更高的抗真菌潜力。抗氧化活性是通过血浆中铁的还原能力来进行的，细胞毒性研究是通过基于四唑鎓的比色法在3T ₃成纤维细胞系中进行的。