Speckle-tracking echocardiography has enabled clinicians to detect changes in myocardial function with more sensitivity than that afforded by traditional diastolic and systolic functional measurements, including left ventricular ejection fraction. Speckle-tracking echocardiography enables evaluation of myocardial strain in terms of strain (percent change in length of a myocardial segment relative to its length at baseline) and strain rate (strain per unit of time). Both measurements have potential for use in diagnosing and monitoring the cardiovascular side effects of cancer therapy. Regional and global strain measurements can independently predict outcomes not only in patients who experience cardiovascular complications of cancer and cancer therapy, but also in patients with a variety of other clinical conditions. This review and case series examine the clinical applications and overall usefulness of speckle-tracking echocardiography in cardio-oncology and, more broadly, in clinical cardiology.

斑点跟踪超声心动图使临床医生能够以比传统舒张和收缩功能测量（包括左心室射血分数）更高的灵敏度检测心肌功能的变化。斑点跟踪超声心动图可以根据应变（心肌节段长度相对于其基线长度的百分比变化）和应变率（每单位时间的应变）来评估心肌应变。这两种测量都有可能用于诊断和监测癌症治疗的心血管副作用。区域和全球应变测量不仅可以独立预测患有癌症和癌症治疗心血管并发症的患者的结果，还可以预测患有各种其他临床状况的患者的结果。