当前位置: X-MOL 学术Tex. Heart Inst. J. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Zinc Deficiency as a Reversible Cause of Heart Failure.
Texas Heart Institute Journal ( IF 0.9 ) Pub Date : 2020-06-17 , DOI: 10.14503/thij-17-6586
Hannah Rosenblum 1 , Behnood Bikdeli 1 , Jeffrey Wessler 1 , Aakriti Gupta 1 , Daniel Louis Jacoby 2
Affiliation  

Zinc, an essential micronutrient, affects the heart by modulating cardiomyocyte oxidative stress and maintaining myocardial structure, among other mechanisms. In cross-sectional studies, patients with heart failure have often had zinc deficiencies, suggesting effects on the ongoing pathogenesis of heart failure. Low plasma and myocardial zinc levels may cause reversible cardiomyopathy in patients who have nutritional deficiencies.

We present the case of a 24-year-old woman with anorexia nervosa and new-onset heart failure whose depressed left ventricular systolic function improved after zinc supplementation. To our knowledge, this is the first report of low plasma zinc levels as the chief cause of cardiomyopathy that resolved after zinc supplementation.



中文翻译:

锌缺乏是心力衰竭的可逆原因。

锌是一种必需的微量营养素,通过调节心肌细胞氧化应激和维持心肌结构等机制影响心脏。在横断面研究中,心力衰竭患者经常缺乏锌,这表明对心力衰竭的持续发病机制有影响。低血浆和心肌锌水平可能会导致营养缺乏的患者发生可逆性心肌病。

我们介绍了一名患有神经性厌食症和新发心力衰竭的 24 岁女性的病例,在补充锌后,其抑制的左心室收缩功能得到改善。据我们所知,这是第一份关于低血浆锌水平作为心肌病的主要原因在补锌后解决的报告。

更新日期:2020-08-23
down
wechat
bug