Applied Physiology, Nutrition, and Metabolism, Ahead of Print.
We studied the effects of age on different physiological parameters, including those derived from (i) maximal cardiopulmonary exercise testing (CPET), (ii) moderate-intensity step transitions, and (iii) tensiomyography (TMG)-derived variables in moderately active women. Twenty-eight women (age, 19 to 53 years), completed 3 laboratory visits, including baseline data collection, TMG assessment, maximal oxygen uptake test via CPET, and a step-transition test from 20 W to a moderate-intensity cycling power output (PO), corresponding to oxygen uptake at 90% gas exchange threshold. During the step transitions, breath-by-breath pulmonary oxygen uptake, near infrared spectroscopy derived muscle deoxygenation (ΔHHb), and beat-by-beat cardiovascular response were continuously monitored. There were no differences observed between the young and middle-aged women in their maximal oxygen uptake and peak PO, while the maximal heart rate (HR) was 12 bpm lower in middle-aged compared with young (p = 0.016) women. Also, no differences were observed between the age groups in τ pulmonary oxygen uptake, ΔHHb, and τHR during on-transients. The first regression model showed that age did not attenuate the maximal CPET capacity in the studied population (p = 0.638), while in the second model a faster τ pulmonary oxygen uptake, combined with shorter TMG-derived contraction time (Tc) of the vastus lateralis (VL), were associated with a higher maximal oxygen uptake (∼30% of explained variance, p = 0.039). In conclusion, long lasting exercise involvement protects against a maximal oxygen uptake and τpulmonary oxygen uptake deterioration in moderately active women. Novelty: Faster τ pulmonary oxygen uptake and shorter Tc of the VL explain 33% of the variance in superior maximal oxygen uptake attainment. No differences between age groups were found in τ pulmonary oxygen uptake, τΔHHb, and τHR during on-transients.

中文翻译：

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持久的运动参与可防止最大摄氧量。中度活跃女性的 VO2 动力学下降。

应用生理学、营养学和代谢，提前出版。
我们研究了年龄对不同生理参数的影响，包括来自 (i) 最大心肺运动测试 (CPET)、(ii) 中等强度阶梯转换和 (iii) 适度活跃女性的肌张力图 (TMG) 衍生变量. 28 名女性（19 至 53 岁）完成了 3 次实验室访问，包括基线数据收集、TMG 评估、通过 CPET 进行的最大摄氧量测试以及从 20 W 到中等强度循环功率输出的阶跃转换测试(PO)，对应于 90% 气体交换阈值下的氧气摄取。在步骤转换期间，持续监测每一次呼吸的肺氧摄取、近红外光谱衍生的肌肉脱氧 (ΔHHb) 和每搏心血管反应。在最大摄氧量和 PO 峰值方面，年轻和中年女性之间没有观察到差异，而中年女性的最大心率 (HR) 比年轻 (p = 0.016) 女性低 12 bpm。此外，在瞬态期间，在 τ 肺氧摄取量、ΔHHb 和 τHR 方面没有观察到年龄组之间的差异。第一个回归模型显示，年龄并未减弱研究人群的最大 CPET 容量（p = 0.638），而在第二个模型中，更快的 τ 肺氧摄取，以及更短的 TMG 衍生的股肌收缩时间 (Tc)外侧肌 (VL) 与更高的最大摄氧量有关（解释方差的 30%，p = 0.039）。综上所述，长期参与运动可以防止中等活跃女性的最大摄氧量和 τ 肺氧摄取量恶化。新颖性：更快的 τ 肺氧摄取量和更短的 VL Tc 解释了 33% 的卓越最大氧摄取量差异。在瞬态期间，在 τ 肺氧摄取、τΔHHb 和 τHR 方面没有发现年龄组之间的差异。