The outer membranes of Gram-negative bacteria provide a permeability barrier to antibiotics and other harmful chemicals. The integrity of this barrier relies on the maintenance of the lipid asymmetry of the outer membrane, and studies of suppressors of a decades-old mutant reveal that YejM plays a key regulatory role and provide a model for the maintenance of this asymmetry.

中文翻译：

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Jan Tschichold的语录“不对称是功能设计的节奏表达”。

革兰氏阴性细菌的外膜为抗生素和其他有害化学物质提供了渗透屏障。该屏障的完整性依赖于外膜脂质不对称性的维持，对数十年历史突变体抑制剂的研究表明，YejM发挥着关键的调节作用，并为维持这种不对称性提供了模型。