ABSTRACT Previous studies examining the dose-response curve in psychotherapy have suggested that 11–19 sessions may be necessary for at least 50% of individuals to show clinically significant improvement. However, this curve has not been examined specifically for cognitive-behavioral therapy (CBT) for anxiety disorders, for which a more rapid recovery curve may be expected. Survival analysis was used to assess the dose-response curve for 201 patients with anxiety disorders who received weekly CBT at an anxiety specialty clinic. The primary outcome measure was the Outcome Questionnaire-45.2, which patients completed prior to each treatment session. Sixty-four percent of the sample achieved reliable change, and this response occurred in approximately five sessions on average. Fifty percent of the sample achieved clinically significant improvement, which occurred in approximately eight sessions on average. The findings suggest that earlier response may be expected in CBT for anxiety disorders, and are discussed in terms of potential ways to further improve response rates for this treatment.

中文翻译：

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焦虑症认知行为疗法的剂量反应曲线

摘要 先前检查心理治疗中的剂量反应曲线的研究表明，至少 50% 的个体可能需要 11-19 个疗程才能显示临床显着改善。然而，该曲线尚未针对焦虑症的认知行为疗法 (CBT) 进行专门检查，可能会出现更快的恢复曲线。生存分析用于评估 201 名在焦虑症专科诊所每周接受 CBT 的焦虑症患者的剂量反应曲线。主要结果测量是结果问卷 45.2，患者在每次治疗之前完成。64% 的样本实现了可靠的变化，这种响应平均发生在大约五个会话中。50% 的样本取得了临床显着改善，平均发生在大约八次。研究结果表明，在 CBT 中可能预期对焦虑症有更早的反应，并讨论了进一步提高这种治疗反应率的潜在方法。