Dear Readers, It is our pleasure to present the third Special Issue on “Plant cells and algae in bioreactors”. This Special Issue has been compiled based of the success of the previous two, published in 2009 and 2014, and presents recent achievements and the state of-the-art in this emerging area of bioprocess engineering. Over the years after the first Special Issue, the interest in microalgae and plant cells as sources of ingredients for the food, pharmaceutical and cosmetic industries, biofuels and many other domains has been increasing continuously. While, the application of microalgae in various areas like environmental clean-up and improvement of bioreactor technologies for micropropagation of economically valuable plant species are also currently receiving considerable attention. Thus, the aim of this Special Issue is to present the most recent achievements and research focused on the current status, advancement, and the prospects for further developments in that field. The advantages of plant in vitro technology for production of bioactive substances are widely discussed. However, the problems with low and unstable yields of target metabolites remain unsolved, despite researchers’ efforts for more than 60 years. This area is addressed in the review presented by Sanchez-Muñoz et al., who have summarized accumulated knowledge about the relationship between in vitro maintenance and epigenetic changes in plant in vitro systems and the prospects of avoiding decline in metabolite production. When optimization of the production processes based on plant in vitro systems is discussed, the elicitation approach cannot be omitted. Halder et al. have contributed with an interesting review presenting their point of view about elicitation as a main tool in enhancing the production of secondary metabolites by hairy roots. The authors have paid special attention to the simultaneous application of more than one elicitor as part of the integrated approach for optimization of secondary metabolites production. Despite the significant progress, bioreactor cultivation and the complex scale-up remain major limitations for the industrial implementation of plant in vitro systems, as far as the choice of bioreactor type largely depends on the type of the

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生物反应器 III 中的植物细胞和藻类

亲爱的读者，我们很高兴推出关于“生物反应器中的植物细胞和藻类”的第三期特刊。本特刊是在前两期成功的基础上编纂而成的，分别于 2009 年和 2014 年出版，并介绍了这个新兴的生物过程工程领域的最新成就和最新技术。在第一期特刊发布后的几年里，人们对微藻和植物细胞作为食品、制药和化妆品行业、生物燃料和许多其他领域的成分来源的兴趣不断增加。同时，微藻在环境净化和改进生物反应器技术等具有经济价值的植物物种的微繁殖等各个领域的应用目前也受到了相当多的关注。因此，本期特刊的目的是介绍最新的成果和研究，重点关注该领域的现状、进展和进一步发展的前景。植物体外技术生产生物活性物质的优势被广泛讨论。然而，尽管研究人员已经努力了 60 多年，但目标代谢物产量低且不稳定的问题仍未得到解决。该领域在 Sanchez-Muñoz 等人提交的评论中得到了解决，他们总结了关于植物体外系统的体外维持和表观遗传变化之间关系的积累知识以及避免代谢物产量下降的前景。在讨论基于植物体外系统的生产过程优化时，不能省略诱导方法。哈尔德等人。贡献了一篇有趣的评论，提出了他们关于诱导作为增强毛状根次生代谢物产生的主要工具的观点。作者特别关注同时应用一种以上的激发物作为优化次级代谢物生产的综合方法的一部分。尽管取得了重大进展，但生物反应器培养和复杂的放大仍然是植物体外系统工业化实施的主要限制，就生物反应器类型的选择而言，很大程度上取决于 作者特别关注同时应用一种以上的激发物作为优化次级代谢物生产的综合方法的一部分。尽管取得了重大进展，但生物反应器培养和复杂的放大仍然是植物体外系统工业化实施的主要限制，就生物反应器类型的选择而言，很大程度上取决于 作者特别关注同时应用一种以上的激发物作为优化次级代谢物生产的综合方法的一部分。尽管取得了重大进展，但生物反应器培养和复杂的放大仍然是植物体外系统工业化实施的主要限制，就生物反应器类型的选择而言，很大程度上取决于