Despite the clinical importance of pollen allergens among Filipinos, few studies delve into the sensitization profiles of Filipinos against pollen allergens. This study determined the sensitization profile of Filipinos to pollen using skin prick test (SPT) and pollen-specific ELISA. Pollen from fifteen selected plant sources was collected and extracted for use in sensitization tests. Volunteers were interviewed for their clinical history prior to blood sampling and SPT. The blood samples collected were assessed using Enzyme-Linked Immunosorbent Assay (ELISA). The best panel of pollen allergens for the skin prick test was Mangifera indica (64%), Acacia auriculiformis (28%), Mimosa spp. (25%) Amaranthus spinosus (22%), Lantana camara (20%), Pilea microphylla (16%) and Dichanthium aristatum (15%). Young adults had more sensitizations to pollen than among early childhood and elderly. There were more allergic subjects that have rhinitis (61%) than asthma (42%) and atopic dermatitis (35%). Pollen-specific IgE levels show low percent reactivity as compared to the skin test with Cocos nucifera obtaining the highest IgE reactivity (21%). Pollen allergens from both arboreal and herbaceous plants used in this study yielded positive reactivities for both skin tests and specific IgE tests.

中文翻译：

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菲律宾人的花粉过敏原皮肤测试和特异性 IgE 反应性：一项基于社区的研究。


尽管花粉过敏原在菲律宾人中具有临床重要性，但很少有研究深入探讨菲律宾人对花粉过敏原的致敏情况。本研究使用皮肤点刺试验 (SPT) 和花粉特异性 ELISA 确定菲律宾人对花粉的过敏情况。收集并提取十五种选定植物来源的花粉用于致敏测试。在抽血和 SPT 之前，对志愿者的临床病史进行了采访。使用酶联免疫吸附测定（ELISA）对收集的血液样本进行评估。用于皮肤点刺测试的最佳花粉过敏原是芒果 (64%)、金合欢 (28%)、含羞草。 (25%) 刺苋 (22%)、马缨丹 (20%)、小叶冷水花 (16%) 和二尖花 (15%)。年轻人比幼儿和老年人对花粉更敏感。患有鼻炎 (61%) 的过敏受试者多于患有哮喘 (42%) 和特应性皮炎 (35%) 的受试者。与获得最高 IgE 反应性 (21%) 的椰子皮肤测试相比，花粉特异性 IgE 水平显示出较低的反应性百分比。本研究中使用的来自树栖和草本植物的花粉过敏原在皮肤测试和特定 IgE 测试中均产生阳性反应。