Cellular reprogramming mainly involves induction of reactivation of genes responsible for nuclear plasticity, a process that can be performed in vitro through production of cloned embryos by somatic cell nuclear transfer or by induction of cells into the pluripotent state through exogenous transcription factor expression. While these techniques are already well known and utilized in mice and rats, their application in other rodent species would be greatly beneficial, especially for conservation purposes. Within the diverse Rodentia order, wild species stand out as they play an important role in balancing the ecosystem by facilitating seed diversion, soil aeration, and consequently, reforestation. Many of these species are currently approaching extinction, and application of techniques, such as nuclear reprogramming, aimed at species conservation and multiplication and to produce stem cells is of interest. Thus, in this review, we aimed to present the evolution and success of nuclear reprogramming, mainly highlighting its potential application for the conservation of wild rodents.

中文翻译：

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Rodentia顺序中的细胞重编程的比较方法。

细胞重编程主要涉及诱导负责核可塑性的基因的重新激活，这一过程可以在体外进行通过体细胞核转移产生克隆的胚胎或通过外源转录因子表达将细胞诱导为多能状态。尽管这些技术已经众所周知，并已在小鼠和大鼠中使用，但将它们应用于其他啮齿动物物种将非常有益，特别是出于保护目的。在不同的啮齿类动物秩序中，野生物种脱颖而出，因为它们通过促进种子转移，土壤通气以及因此的植树造林在平衡生态系统中发挥重要作用。这些物种中的许多目前正在灭绝，而针对物种保护和繁殖并产生干细胞的技术应用（如核重编程）则受到关注。因此，在这篇评论中