The aim of the present study was to investigate the frequency and clinical features of Guillain-Barré syndrome (GBS) with hyperCKemia. We retrospectively identified 139 patients with GBS at 2 teaching hospitals in South Korea. We excluded patients with Miller-Fisher syndrome (n = 19), acute bulbar palsy (n = 3), and those whose serum creatine kinase (CK) levels were not measured (n = 45). Twelve of 72 patients (16.7%) had transient hyperCKemia, defined as serum CK ≥300 IU/L. The frequency of male sex and non-demyelinating electrodiagnostic features were higher in patients with hyperCKemia than those without. Transient hyperCKemia, occasionally seen in patients with GBS may be associated with the non-demyelinating subtype.

中文翻译：

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吉兰-巴雷综合征中的高CK血症

本研究的目的是调查伴有高CK血症的格林-巴利综合征（GBS）的发生频率和临床特征。我们回顾性地确定了韩国 2 家教学医院的 139 名 GBS 患者。我们排除了 Miller-Fisher 综合征 (n = 19)、急性延髓麻痹 (n = 3) 和未测量血清肌酸激酶 (CK) 水平的患者 (n = 45)。72 名患者中有 12 名 (16.7%) 出现一过性高 CK 血症，定义为血清 CK ≥ 300 IU/L。高CK血症患者男性和非脱髓鞘电诊断特征的频率高于非脱髓鞘患者。短暂性高CK血症，偶尔见于 GBS 患者，可能与非脱髓鞘亚型有关。