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Antiviral Activity of Nanomaterials against Coronaviruses.
Macromolecular Bioscience ( IF 4.6 ) Pub Date : 2020-08-11 , DOI: 10.1002/mabi.202000196
Wali Muhammad 1 , Zihe Zhai 1 , Changyou Gao 1
Affiliation  

One of the challenges facing by world nowadays is the generation of new pathogens that cause public health issues. Coronavirus (CoV) is one of the severe pathogens that possess the RNA (ribonucleic acid) envelop, and extensively infect humans, birds, and other mammals. The novel strain “SARS‐CoV‐2” (severe acute respiratory syndrome coronavirus‐2) causes deadly infection all over the world and presents a pandemic situation nowadays. The SARS‐CoV‐2 has 40 different strains that create a worrying situation for health authorities. The virus develops serious pneumonia in infected persons and causes severe damage to the lungs. There is no vaccine available for this virus up to present. To cure this type of infections by making vaccines and antiviral drugs is still a major challenge for researchers. Nanotechnology covering a multidisciplinary field may find the solution to this lethal infection. The interaction of nanomaterials and microorganisms is considered as a potential treatment method because the nanomaterials owe unique physicochemical properties. The aim of this review is to present an overview of previous and recent studies of nanomaterials against coronaviruses and to provide possible new strategies for upcoming research using the nanotechnology platform.

中文翻译:

纳米材料对冠状病毒的抗病毒活性。

当今世界面临的挑战之一是导致公共卫生问题的新病原体的产生。冠状病毒(CoV)是一种严重的病原体,具有RNA(核糖核酸)包膜,并广泛感染人类,鸟类和其他哺乳动物。新型菌株“ SARS-CoV-2”(严重的急性呼吸系统综合症冠状病毒-2)在世界范围内造成致命感染,并在当今呈大流行状态。SARS-CoV-2有40种不同的菌株,给卫生部门带来了令人担忧的情况。该病毒在感染者中发展为严重的肺炎,并严重损害肺部。到目前为止,尚无针对该病毒的疫苗。通过生产疫苗和抗病毒药物来治愈这类感染仍然是研究人员面临的主要挑战。涵盖多学科领域的纳米技术可能找到这种致命感染的解决方案。纳米材料与微生物的相互作用被认为是一种潜在的治疗方法,因为纳米材料具有独特的理化特性。这篇综述的目的是概述针对冠状病毒的纳米材料的以前和最近的研究,并为使用纳米技术平台进行未来研究提供可能的新策略。
更新日期:2020-10-12
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