Y‐TZP containing Ca₂P₂O₇ are promising bioceramics with potential applications in dental implants and dentistry. These ceramics were developed by the introduction of a refractory sol‐gel derived CaO‐P₂O₅‐SiO₂ bioglass into Y‐TZP; Ca₂P₂O₇, and ZrSiO₄ phases were formed in situ after sintering. The aging process of Y‐TZP with different glass additions was studied. The effect of glass addition on the flexural strength and osteoblastic cell response of non‐aged and aged Y‐TZP was investigated. Y‐TZP exhibited the most pronounced tetragonal (t) to monoclinic (m) transformation of zirconia (ZrO₂) during aging; the addition of glass contents between 5 and 20 vol% improved the aging resistant of Y‐TZP. Y‐TZP flexural strength markedly decreased with increasing aging time; in contrast, the ceramics with glass did not alter their flexural strength upon aging. An increase in the Ca₂P₂O₇ content with increasing glass up to 10 vol%, promoted both the cell viability and the osteogenic differentiation of UMR‐106 cells on non‐aged and aged samples. The high micro‐roughness of Y‐TZP with 20 vol% glass after aging, limited the proliferation and the osteogenic potential of the cultures. Y‐TZP with 10 vol% glass had the best combination of properties in terms of flexural strength and osteoblast cell response.

中文翻译：

---

添加生物玻璃的Y‐TZP的老化行为及其对弯曲强度和成骨细胞反应的影响

含Ca ₂ P ₂ O _7的Y‐TZP是有前途的生物陶瓷，在牙科植入物和牙科中具有潜在的应用前景。这些陶瓷是通过在Y‐TZP中引入难熔溶胶凝胶衍生的CaO‐P ₂ O ₅ ‐ SiO ₂生物玻璃而开发的。Ca ₂ P ₂ O ₇和ZrSiO ₄烧结后原位形成相。研究了不同玻璃添加量的Y-TZP的时效过程。研究了玻璃添加对未老化和老化的Y-TZP的弯曲强度和成骨细胞反应的影响。在老化过程中，Y‐TZP表现出最明显的氧化锆（ZrO ₂）四方（t）到单斜晶（m）转变；添加5至20 vol％的玻璃含量可改善Y‐TZP的耐老化性。Y-TZP弯曲强度随着时效时间的增加而显着降低；相反，带有玻璃的陶瓷在老化时不会改变其弯曲强度。Ca ₂ P ₂ O _7的增加随玻璃含量增加至10 vol％含量，可促进细胞活力和未老化和老化样品中UMR-106细胞的成骨分化。Y-TZP在20vol％的玻璃中老化后具有很高的显微粗糙度，限制了培养物的增殖和成骨潜能。就抗弯强度和成骨细胞反应而言，含10％（体积）玻璃的Y-TZP具有最佳的性能组合。