Inflammatory conditions of the esophagus: an update,Annals of the New York Academy of Sciences

当前位置： X-MOL 学术 › Ann. N. Y. Acad. Sci. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Inflammatory conditions of the esophagus: an update
Annals of the New York Academy of Sciences ( IF 4.1 ) Pub Date : 2020-08-11 , DOI: 10.1111/nyas.14450
Mikhail Lisovsky ₁

Affiliation

A variety of inflammatory disorders involve the esophagus. This commentary discusses the pathology of some forms of esophagitis, with an emphasis on recent developments. The initial section focuses on some common forms of nonreflux esophagitis, including lymphocytic esophagitis and eosinophilic esophagitis. Recent studies suggest that lymphocytic esophagitis may be associated with esophageal motility disorders and gastroesophageal reflux disease. Immunophenotypic features of intraepithelial lymphocytes may be helpful in distinguishing these conditions. Updates on the criteria and the limitations of histologic approach to the diagnosis of eosinophilic esophagitis are presented and new diagnostic adjuncts are discussed. In the remaining section, novel entities, such as IgG4‐related esophagitis, are discussed. IgG4‐related esophagitis has been recognized as a cause of esophageal lymphoplasmacytic inflammation. Increased understanding of esophageal inflammation remains an important goal that likely will lead to new approaches in the therapy of inflammatory esophageal diseases.

中文翻译：

食道的炎症状况：更新

多种炎症性疾病涉及食道。这篇评论讨论了某些形式的食管炎的病理，重点介绍了最近的发展。初始部分侧重于非反流性食管炎的一些常见形式，包括淋巴细胞性食管炎和嗜酸性粒细胞性食管炎。最近的研究表明，淋巴细胞性食管炎可能与食管动力障碍和胃食管反流病有关。上皮内淋巴细胞的免疫表型特征可能有助于区分这些疾病。更新了诊断嗜酸性粒细胞性食管炎的组织学方法的标准和局限性，并讨论了新的诊断辅助手段。在剩下的部分中，将讨论新的实体，例如 IgG4 相关的食管炎。IgG4 相关性食管炎已被认为是导致食管淋巴浆细胞炎症的一个原因。增加对食管炎症的了解仍然是一个重要的目标，可能会导致治疗炎症性食管疾病的新方法。

更新日期：2020-08-11

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11