Chronic oral azithromycin therapy improves clinical outcomes in people with cystic fibrosis (CF), and is recommended for treatment of CF lung disease. Azithromycin is categorized as pregnancy class B. The data for risk of congenital malformations associated with use of azithromycin during pregnancy ranges from no risk to a small increased risk. As with other chronic medications used to treat CF, potential risk to the infant of use of azithromycin during pregnancy must be weighed against the potential risk to the mother of treatment discontinuation. Women with CF considering pregnancy while on chronic azithromycin should be counseled regarding potential risks and benefits.

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关于妊娠期阿奇霉素安全性的担忧 - 与囊性纤维化女性的相关性

慢性口服阿奇霉素治疗可改善囊性纤维化 (CF) 患者的临床结果，并推荐用于治疗 CF 肺病。阿奇霉素被归类为妊娠 B 类。妊娠期间与使用阿奇霉素相关的先天性畸形风险的数据范围从无风险到小幅增加的风险。与用于治疗 CF 的其他慢性药物一样，必须权衡婴儿在怀孕期间使用阿奇霉素的潜在风险与停止治疗对母亲的潜在风险。应告知 CF 女性在服用长期阿奇霉素时考虑怀孕的潜在风险和益处。