The process of drug discovery and development in the world over a recent year has been increasingly shaped by the formulaic approaches and natural products, prioritized by popular pharmaceutical industries. In many countries like Nepal, Randia dumetorum (Maidal) is one of the popular alternatives for overcoming various symptoms such as acidity, food poisoning ulcers, diabetes and ulcers. It has been using by the people because of its wide range of therapeutic uses. Though, the considerable research had been conducted to reveal the biologically active compounds and its pharmacological effect, the rich constituent of this plant and its major biological perspective was yet to be studied comprehensively. Accordingly, the main focus of this study was the alpha amylase inhibition of methanolic extracts obtained from leaves and barks of Randia dumetorum plant. The plant extracts were obtained by dissolving dried plant with 100% methanol overnight and evaporating to the dryness. The obtained plant extract was used to study mentioned biological activities. The results obtained showed that the extract obtained from leaves and barks showed antioxidant and alpha amylase inhibition activities. This research can be helpful to discover new types of therapeutics in the future.

中文翻译：

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兰R叶和树皮的抗氧化和体外α-淀粉酶抑制活性

近年来，世界范围内的药物发现和开发过程已逐渐受到配方化方法和天然产品的影响，受到流行制药业的重视。在许多国家（如尼泊尔），Randia dumetorum（Maidal）是克服各种症状（例如酸度，食物中毒性溃疡，糖尿病和溃疡）的流行替代品之一。由于其广泛的治疗用途，人们一直在使用它。尽管已经进行了大量的研究以揭示其生物活性化合物及其药理作用，但是该植物的丰富成分及其主要生物学观点尚待全面研究。因此，这项研究的主要重点是抑制从Randia dumetorum植物的叶子和树皮获得的甲醇提取物的α淀粉酶。通过将干燥的植物用100％甲醇溶解过夜并蒸发至干而获得植物提取物。获得的植物提取物用于研究上述生物活性。获得的结果表明，从叶和树皮获得的提取物显示出抗氧化剂和α淀粉酶的抑制活性。这项研究可能有助于发现未来的新型治疗方法。获得的结果表明，从叶和树皮获得的提取物显示出抗氧化剂和α淀粉酶的抑制活性。这项研究可能有助于发现未来的新型治疗方法。获得的结果表明，从叶和树皮获得的提取物显示出抗氧化剂和α淀粉酶的抑制活性。这项研究可能有助于发现未来的新型治疗方法。