Fe₃O₄@FAp@Ni was synthesized and has been used as a new and efficient recyclable magnetic nanocatalyst for the synthesis of polyfunctional indole-pyrido[2,3-d]pyrimidine hybrids. The Fe₃O₄@FAp@Ni was conveniently separated by an external magnet and could be reused at least six times without any appreciable change in catalytic activity. This novel protocol furnished the products in high to excellent yield (75–95%) and short reaction time. The antibacterial properties of the products were also evaluated and some of them exhibited promising activities.

中文翻译：

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镍掺入氟磷灰石包裹的氧化铁纳米催化剂轻松合成多官能团吲哚-吡啶并[2,3-d]嘧啶杂化物及其抗菌活性的研究

合成了Fe ₃ O ₄ @ FAp @ Ni，并已将其用作合成多官能团吲哚-吡啶并[2,3- d ]嘧啶杂化物的新型高效可循环磁性纳米催化剂。Fe ₃ O ₄ @ FAp @ Ni可以方便地通过外部磁体分离，并且可以重复使用至少六次，而催化活性没有任何明显的变化。这一新颖的方案为产品提供了高至优异的收率（75–95％），反应时间短。还评估了产品的抗菌性能，其中一些产品显示出令人鼓舞的活性。