Plasma endocannabinoids and cannabimimetic fatty acid derivatives are altered in gastroparesis: A sex- and subtype-dependent observation.,Neurogastroenterology & Motility

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Plasma endocannabinoids and cannabimimetic fatty acid derivatives are altered in gastroparesis: A sex- and subtype-dependent observation.
Neurogastroenterology & Motility ( IF 3.5 ) Pub Date : 2020-08-10 , DOI: 10.1111/nmo.13961
Mohammad Bashashati ₁ , Emma Leishman ₂ , Heather Bradshaw ₂ , Solmaz Sigaroodi _{1,

3} , Eric Tatro ₁ , Tamis Bright ₄ , Richard McCallum ₁ , Irene Sarosiek ₁

Affiliation

Gastroparesis (GP) is a motility disorder of the stomach presenting with upper gastrointestinal symptoms in the setting of delayed gastric emptying. Endocannabinoids are involved in the regulation of GI function including motility. However, their role in the pathophysiology of GP has not been sufficiently investigated. Our goal was to compare the circulating levels of endocannabinoids and cannabimimetic fatty acid derivatives in GP versus control subjects.

中文翻译：

血浆内源性大麻素和大麻素脂肪酸衍生物在胃轻瘫中发生改变：性别和亚型依赖性观察。

胃轻瘫 (GP) 是一种胃动力障碍，在胃排空延迟的情况下出现上消化道症状。内源性大麻素参与包括运动在内的胃肠功能的调节。然而，它们在 GP 病理生理学中的作用尚未得到充分研究。我们的目标是比较 GP 与对照受试者中内源性大麻素和大麻素脂肪酸衍生物的循环水平。

更新日期：2020-08-10

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