CRISPR‐cas technology is being incorporated into undergraduate biology curriculum through lab experiences to immerse students in modern technology that is rapidly changing the landscape of science, medicine and agriculture. We developed and implemented an educational module that introduces students to CRISPR‐cas technology in a Genetic course and an Advanced Genetics course. Our primary teaching objective was to immerse students in the design, strategy, conceptual modeling, and application of CRISPR‐cas technology using the current research claim of the modification of the CCR5 gene in twin girls. This also allowed us to engage students in an open conversation about the bioethical implications of heritable germline and non‐heritable somatic genomic editing. We assessed student‐learning outcomes and conclude that this learning module is an effective strategy for teaching undergraduates the fundamentals and application of CRISPR‐cas gene editing technology and can be adapted to other genes and diseases that are currently being treated with CRISPR‐cas technology.

中文翻译：

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“设计师宝贝？！” 围绕 CCR5 基因构建的基于 CRISPR 的本科生学习模块

CRISPR-cas 技术正通过实验室体验被纳入本科生物课程，让学生沉浸在正在迅速改变科学、医学和农业领域的现代技术中。我们开发并实施了一个教育模块，在遗传课程和高级遗传学课程中向学生介绍 CRISPR-cas 技术。我们的主要教学目标是利用当前关于双胞胎女孩 CCR5 基因修饰的研究主张，让学生沉浸在 CRISPR-cas 技术的设计、策略、概念建模和应用中。这也使我们能够让学生参与关于可遗传种系和非可遗传体细胞基因组编辑的生物伦理意义的公开对话。