Fungi are heterotrophic organisms possessing cryptic lifestyles and have an individual hierarchy in the evolution of microorganisms on earth. Out of which, Keratinophilic fungi are allied molds that produce keratinase enzymes and diminish the keratin matters in or on the soil. Fifty soil samples were collected from various sites of Jaipur district, India to analyze incidence of keratinophilic fungi. Out of 162 isolates, a total of 24 keratinophilic fungal species of 13 genera were recovered, including Trichophyton sp. (17.90%), Aspergillus sp. (17.90%), Chrysosporium sp. (14.81%). Selective keratinophilic fungi were also discussed about phylogenetic studies. In multiple sequence alignment of sequences, species were reported to have closest relationships between teleomorphic and anamorphic form of keratinophilic fungi which exhibited a reason for phase changes between geophilic and dermatophytic fungi by accident or opportunistic where they may cause infections in both humans and animals on the opportunity. In the anti-fungal activity, Eucalyptus globulus (Inhibition Zone: 23.5 mm; Activity Index: 0.82) and Ocimum tenuiflorum (Inhibition Zone: 20.75 mm; Activity Index: 1.46) were inscribed to dispense a greater potential of antifungal activity against all selected keratinophilic fungi.

真菌是异养生物，具有隐秘的生活方式，并且在地球微生物的进化中具有单独的等级制度。其中，角质亲和真菌是产生霉菌蛋白酶和减少土壤中或土壤中角蛋白物质的同盟霉菌。从印度斋浦尔地区的不同地点收集了五十份土壤样品，以分析嗜角蛋白真菌的发生率。在162种分离物中，共回收了13个属的24种角蛋白亲和真菌，包括毛癣菌（Trichophyton sp。）。（17.90％），曲霉菌。（17.90％），金孢菌属sp。（14.81％）。还讨论了有关系统发育研究的选择性角蛋白亲和真菌。在序列的多序列比对中，据报道，物种与角质亲和性真菌的变型和变型形式之间具有最密切的关系，这表明偶然或偶然的嗜地性和皮肤致病性真菌之间相变的原因，它们可能在人类和动物身上引起感染。机会。在抗真菌活性中，球状桉树（抑制区：23.5 mm；活性指数：0.82）和tenciflorum（抑制区：20.75 mm；活性指数：1.46）被铭记为对所有选定的角蛋白亲和性具有更大的抗真菌活性潜力菌类。