Objectives

We investigate the relationship between the severity of vascular disease and epicardial adipose tissue thickness(EAT-t) and the neutrophil/lymphocyte (NEU/LY) ratio in acute stroke patients.

Methods

Seventy-six patients and 38 healthy controls were included in the study. Strokes were divided into three groups: lacunar infarction, middle cerebral artery infarction (MCA), and other arterial infarcts. Patients were assessed using the GCS (Glasgow coma scale) and NIHSS (National Institutes of Health Stroke Scale) scales. In addition to laboratory measurements, EAT-t was evaluated in all patients by using echocardiography.

Results

The EAT-t value and NEU/LY ratio were higher in the patient group than in the control group. The MCA group was found to have a significantly higher NEU/LY ratio than the lacuna group (p = 0.017) as well as the other patient (p = 0.025) group. There was a positive correlation of NIHSS score with EAT-t (r = 0.291; p = 0.013), and NEU/LY ratio (r = 0.289; p = 0.014).

Conclusion

The EAT-t and NEU/LY ratio were high in patients with acute ischemic stroke patients. The higher ratio of NEU/LY compared to other infarcts in the MCA group. These findings support the relationship between acute ischemic stroke severity and inflammation .

中文翻译：

---

急性闭塞性脑血管疾病的心外膜脂肪厚度和中性粒细胞淋巴细胞比率

目标

我们调查了急性卒中患者血管疾病的严重程度与心外膜脂肪组织厚度（EAT-t）和中性粒细胞/淋巴细胞（NEU / LY）比率之间的关系。

方法

本研究包括76位患者和38位健康对照。中风分为三组：腔隙性梗塞，脑中动脉梗塞（MCA）和其他动脉梗塞。使用GCS（格拉斯哥昏迷量表）和NIHSS（美国国立卫生研究院卒中量表）量表对患者进行评估。除了实验室测量，还通过超声心动图对所有患者的EAT-t进行了评估。

结果

患者组的EAT-t值和NEU / LY比值高于对照组。发现MCA组的NEU / LY比腔隙组（p  = 0.017）以及其他患者（p  = 0.025）组明显更高。NIHSS评分与EAT-t（r  = 0.291; p  = 0.013）和NEU / LY比（r  = 0.289; p  = 0.014）呈正相关。

结论

急性缺血性中风患者的EAT-t和NEU / LY比很高。与MCA组中其他梗死相比，NEU / LY的比率更高。这些发现支持急性缺血性脑卒中严重程度与炎症之间的关系。