Abstract

New derivatives of a number of aryloxy and arylaminopropanehydrazides were synthesized. Their heterocyclization under the action of carbon disulfide and potassium hydroxide and subsequent alkylation of the resulting 2-thioxo-1,3,4-oxadiazole ring, the corresponding S-substituted products were obtained. The reaction of the starting hydrazides with arylaldehydes and pentane-2,4-dione afforded their N′-arylidene and N′-(4-oxopentan-2-ylidene) derivatives. In preliminary laboratory tests, the synthesized compounds showed a pronounced stimulating effect on plant growth. Their activity was 44–95% compared with heteroauxin.

中文翻译：

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基于芳氧基和芳基氨基丙酰肼的潜在生物活性化合物的合成

摘要

合成了许多芳氧基和芳基氨基丙酰肼的新衍生物。它们在二硫化碳和氢氧化钾的作用下杂环化，然后将所得的2-硫代-1,3,4-恶二唑环烷基化，得到相应的S-取代产物。起始酰肼与芳基醛和戊烷-2,4-二酮的反应得到其N'-亚芳基和N '-（4-氧戊丹-2-亚烷基）衍生物。在初步的实验室测试中，合成的化合物对植物生长显示出明显的刺激作用。与异生长素相比，它们的活性为44–95％。