The rapid community-spread of novel human coronavirus 2019 (nCOVID19 or SARS-Cov2) and morbidity statistics has put forth an unprecedented urge for rapid diagnostics for quick and sensitive detection followed by contact tracing and containment strategies, especially when no vaccine or therapeutics are known. Currently, quantitative real-time polymerase chain reaction (qRT-PCR) is being used widely to detect COVID-19 from various types of biological specimens, which is time-consuming, labor-intensive and may not be rapidly deployable in remote or resource-limited settings. This might lead to hindrance in acquiring realistic data of infectivity and community spread of SARS-CoV-2 in the population. This review summarizes the existing status of current diagnostic methods, their possible limitations, and the advantages of biosensor-based diagnostics over the conventional ones for the detection of SARS-Cov-2. Novel biosensors used to detect RNA-viruses include CRISPR-Cas9 based paper strip, nucleic-acid based, aptamer-based, antigen-Au/Ag nanoparticles-based electrochemical biosensor, optical biosensor, and Surface Plasmon Resonance. These could be effective tools for rapid, authentic, portable, and more promising diagnosis in the current pandemic that has affected the world economies and humanity. Present challenges and future perspectives of developing robust biosensors devices for rapid, scalable, and sensitive detection and management of COVID-19 are presented in light of the test-test-test theme of the World Health Organization (WHO).

新型人类冠状病毒 2019（nCOVID19 或 SARS-Cov2）在社区中的快速传播和发病率统计数据对快速诊断提出了前所未有的要求，以实现快速、灵敏的检测，然后进行接触者追踪和遏制策略，特别是在尚无疫苗或治疗方法的情况下。目前，定量实时聚合酶链反应（qRT-PCR）被广泛用于从各种类型的生物标本中检测COVID-19，该方法耗时、劳动密集型，并且可能无法在偏远或资源丰富的地区快速部署。有限的设置。这可能会阻碍获取 SARS-CoV-2 在人群中的感染性和社区传播的实际数据。本综述总结了当前诊断方法的现状、可能的局限性，以及基于生物传感器的诊断方法相对于传统方法检测 SARS-Cov-2 的优势。用于检测RNA病毒的新型生物传感器包括基于CRISPR-Cas9的纸条、基于核酸、基于适体、基于抗原-Au/Ag纳米粒子的电化学生物传感器、光学生物传感器和表面等离子共振。在当前影响世界经济和人类的大流行中，这些可能成为快速、真实、便携和更有希望的诊断的有效工具。根据世界卫生组织 (WHO) 的测试主题，提出了开发强大的生物传感器设备以快速、可扩展且灵敏地检测和管理 COVID-19 的当前挑战和未来前景。