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Systematic Assessment of Mycobacterium avium Subspecies Paratuberculosis Infections from 1911-2019: A Growth Analysis of Association with Human Autoimmune Diseases.
Microorganisms ( IF 4.1 ) Pub Date : 2020-08-10 , DOI: 10.3390/microorganisms8081212
Temitope C Ekundayo 1, 2, 3 , Anthony I Okoh 1, 2
Affiliation  

Mycobacterium avium subsp. paratuberculosis (MAP) is an understudied pathogen worldwide with continuous implications in human autoimmune diseases (ADs). The awareness of MAP appears to be low in many places and its research is at infant stage in many countries. The lack of worldwide coverage of the MAP research landscape calls for urgent research attention and prioritization. This present study aimed to assess MAP global research productivity with an emphasis on its implications in ADs via bibliometric and growth analytic frameworks from authors, countries, institutions, international, disciplines and collaboration network perspectives. MAP primary articles were retrieved from the Scopus database and the Web of Science from 1911 to 2019 via title-specific algorithm. Analytic results of dataset yielded a total of 3889 articles from 581 journals and 20.65 average citations per documents. The annual growth rate of MAP research for the period was 6.31%. Based on a country’s productivity (articles (%), freq. of publication (%)), the USA (887 (22.81%), 26.72%), and Australia (236 (6.07%), 6.07%) ranked the top 2 countries but Egypt and Germany had the highest average growth rate (AGR, 170%) in the last 3 years. MAP studies are generally limited to Europe, Australia, Asia, South America and few nations in Africa. It had positive growth rate (30%–100%) in relation to type 1 diabetes mellitus and rheumatoid arthritis ADs; food science and technology, immunology, agriculture, pathology, and research and experimental medicine, wildlife, environments, virulence, disease resistance, meat and meat products, osteopontin, waste milk and slurry/sludge digestion subjects; but negative growth (−130% to −30%) in ulcerative colitis and Parkinson’s disease and no growth in multiple sclerosis, sarcoidosis, thyroid disorders, psoriasis, and lupus. The mapping revealed a gross lack of collaboration networking in terms of authorship, (intra- and inter-) nationally and institutionally with a generalized collaboration index of 1.82. In conclusion, inadequate resources-, knowledge- and scientific-networking hampered growth and awareness of MAP research globally. The study recommends further research to strengthen evidence of MAP’s epidemiologic prevalence in ADs and proffer practical solution(s) for drug development and point-of-care diagnostics amongst other extended themes.

中文翻译:

禽分枝杆菌亚种副结核菌感染从1911年至2019年的系统评估:与人类自身免疫性疾病的关联性增长分析。

鸟分枝杆菌亚种 副结核病(MAP)是世界范围内被研究不足的病原体,对人类自身免疫性疾病(ADs)具有持续影响。在许多地方,人们对MAP的认识似乎很低,在许多国家,它的研究还处于起步阶段。缺乏MAP研究领域的全球报道,迫切需要关注研究并确定优先次序。本研究旨在通过作者,国家,机构,国际,学科和协作网络角度的文献计量和增长分析框架,评估MAP全球研究生产力,重点在于其对AD的影响。通过标题专有算法从1911年至2019年从Scopus数据库和Web of Science检索MAP的主要文章。数据集的分析结果产生了来自581种期刊的3889篇文章,每个文档的平均引用率为20.65。在此期间,MAP研究的年增长率为6.31%。根据一个国家的生产力(文章(%),出版频率(%)),美国(887个(22.81%),26.72%)和澳大利亚(236个(6.07%),6.07%)排名前两位但是埃及和德国在过去三年中的平均增长率最高(AGR为170%)。MAP研究通常限于欧洲,澳大利亚,亚洲,南美和非洲的少数几个国家。与1型糖尿病和类风湿关节炎ADs相比,其增长率为正(30%–100%);食品科学技术,免疫学,农业,病理学以及研究和实验医学,野生生物,环境,毒力,抗病性,肉和肉制品,骨桥蛋白,废牛奶和浆液/污泥消化科目;但溃疡性结肠炎和帕金森氏病呈负增长(-130%至-30%),多发性硬化症,结节病,甲状腺疾病,牛皮癣和狼疮无增长。该图显示,在国家和机构范围内(内部和内部)的作者身份方面,协作网络完全缺乏,广义协作指数为1.82。总之,资源,知识和科学网络的不足阻碍了全球MAP研究的增长和认识。这项研究建议进一步研究,以加强MAP在AD中的流行病学证据,并为药物开发和即时诊断提供其他实用的解决方案。该图显示,在国家和机构范围内(内部和内部)的作者身份方面,协作网络完全缺乏,广义协作指数为1.82。总之,资源,知识和科学网络的不足阻碍了全球MAP研究的增长和认识。这项研究建议进一步研究,以加强MAP在AD中的流行病学证据,并为药物开发和即时诊断提供其他实用的解决方案。该图显示,在国家和机构范围内(内部和内部)的作者身份方面,协作网络完全缺乏,广义协作指数为1.82。总之,资源,知识和科学网络的不足阻碍了全球MAP研究的增长和认识。这项研究建议进一步研究,以加强MAP在AD中的流行病学证据,并为药物开发和即时诊断提供其他实用的解决方案。
更新日期:2020-08-10
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