Polyether ionophore antibiotics such as Lasalocid A, Salinomycin and Semduramicin, which are used a lot in veterinary medicine, have high toxicity among other antibiotics. They cannot be eliminated by conventional wastewater treatment and leak into surface and ground water which can have detrimental damage on aquatic environment. Membrane processes like ultrafiltration can be a solution as tertiary and advanced treatment for this issue. Unfortunately, they can be easily fouled by dissolved substances. In this study, poly(amidoamine) (PAMAM) dendrimers were used as novel antifouling agents and chemically coated on the amidoximated membranes with different half-generations (G0-G2.5). New membranes exhibited great performances in the treatment of pharmaceutical wastewater with these antibiotics. G2.5 PAMAM-coated ultrafiltration membranes were selected as optimum membranes with 120.4 L/m².h of pure water flux, 91.3% of Semduramicin rejection, low contact angle (51.2°) and zeta potential (-56.1 mV). The flux profiles of these membranes revealed that the flux reduction does not occur after 1–1.5 h of filtration. These profiles were fitted by power law model. In addition to the surface charge and pore size, the branches of dendrimers, which had negative charges, acted great roles during the filtration.

兽药中大量使用的聚醚离子载体抗生素，例如Lasalocid A，Salinomycin和Semduramicin，在其他抗生素中具有很高的毒性。它们不能通过常规废水处理消除，并泄漏到地表水和地下水中，这会对水生环境造成有害损害。诸如超滤之类的膜工艺可以作为此问题的第三级和高级处理的解决方案。不幸的是，它们很容易被溶解的物质污染。在这项研究中，聚（酰胺基胺）（PAMAM）树状聚合物被用作新型防污剂，并化学涂覆在具有不同半衰期（G0-G2.5）的氨基a肟化膜上。新的膜在用这些抗生素处理制药废水中表现出出色的性能。G2。² h的纯净水通量，91.3％的Semduramicin截留率，低接触角（51.2°）和zeta电位（-56.1 mV）。这些膜的通量曲线表明，过滤1–1.5 h后通量没有降低。这些配置文件由幂定律模型拟合。除表面电荷和孔径外，带负电荷的树枝状聚合物的分支在过滤过程中起着重要作用。