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Models for Immuno-oncology Research.
Cancer Cell ( IF 48.8 ) Pub Date : 2020-08-10 , DOI: 10.1016/j.ccell.2020.07.010


The interactions between cancer cells and immune cells are complex and context dependent. Choosing the right model to study these interactions is a crucial step in the development of immunotherapies. From cell co-cultures to organoids, organs-on-chip, and a variety of mouse models, experts share their model of choice for immuno-oncology research and discuss their strengths and caveats.



中文翻译:

免疫肿瘤学研究模型。

癌细胞和免疫细胞之间的相互作用是复杂的,并且取决于环境。选择正确的模型来研究这些相互作用是免疫疗法发展的关键步骤。从细胞共培养到类器官,芯片上的器官以及各种小鼠模型,专家们分享了他们在免疫肿瘤学研究中选择的模型,并讨论了它们的优势和警告。

更新日期:2020-08-10
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