Objective: To construct a porous titanium-based implant with good biocompatibility and appropriate modulus matching human bone. Methods: Porous titanium with triangular, quadrangular and hexagonal prism as structure monomer were constructed by 3D printing, and the effects of pore structures on the mechanical and biological properties of materials were investigated by computational simulation, mechanical property tests and cell adhesion and proliferation tests. Results: The modulus of titanium with quadrangular monomer was the closest to that of human bone. Besides, the quadrangular sample also shows the best cytocompatibility, presenting the most promotion effects on cell proliferation. Conclusion: The porous titanium constructed by quadrangular monomer has the best comprehensive performance, and the relevant results can provide data support for the design and clinical application of 3D printing porous titanium-based implants.

目的：构建具有良好生物相容性和与人体骨骼相适应的模量的多孔钛基植入物。方法：通过3D打印技术，以三角形，四边形和六边形棱柱为结构单体，制备多孔钛，并通过计算模拟，力学性能测试以及细胞粘附和增殖测试研究孔结构对材料力学和生物学性能的影响。结果：钛与四角形单体的模量最接近人体骨骼。此外，四角形样品还显示出最佳的细胞相容性，对细胞增殖表现出最大的促进作用。结论：由四角形单体构成的多孔钛具有最佳的综合性能，