Abstract

Purpose

To evaluate the safety and effect of microwave ablation (MWA) compared with transcatheter arterial embolization (TAE) for the treatment of large hepatic hemangiomas.

Materials and methods

A total of 135 patients with symptomatic or/and enlarging hepatic hemangiomas (5–10 cm) from two centers underwent either MWA (n = 82) or TAE (n = 53) as first-line treatment. We compared the two groups in terms of radiologic response, clinical response, operative time, postoperative analgesic requirements, hospital stay and complications.

Results

MWA had a significantly higher rate of complete radiologic response (89.0% vs. 37.7%, p<.001) and complete clinical response (88.6% vs. 69.2%, p=.046), fewer minor complications (43.9% vs. 66.0%, p=.019), shorter time of using analgesics (p<.001) and shorter hospital stays (p=.003) than did TAE. The operative time and major complications were comparable between the two groups.

Conclusion

Both MWA and TAE are safe and effective in treating patients with large hepatic hemangiomas. MWA had a higher rate of complete response than did TAE, and it was associated with fewer minor complications, faster recovery and shorter hospital stay.

中文翻译：

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微波消融与经导管动脉栓塞治疗大型肝血管瘤：临床结果。

摘要

目的

为了评估微波消融（MWA）与经导管动脉栓塞术（TAE）相比治疗大面积肝血管瘤的安全性和效果。

材料和方法

 一线治疗共有135名来自两个中心的症状性或/和扩大性肝血管瘤（5-10 cm）患者接受了MWA（n  = 82）或TAE（n = 53）治疗。我们在放射学反应，临床反应，手术时间，术后镇痛要求，住院时间和并发症方面比较了两组。

结果

MWA的完全放射学应答率（89.0％vs. 37.7％，p <.001）和完全临床应答率（88.6％vs. 69.2％，p = .046）显着更高，较小的并发症较少（43.9％vs. 66.0） ％，p = .019），使用镇痛药的时间短（p <.001），住院时间短（p = .003）。两组的手术时间和主要并发症相似。

结论

MWA和TAE均可安全有效地治疗大肝血管瘤患者。与TAE相比，MWA的完全缓解率更高，并且与较小的并发症，更快的康复和更短的住院时间相关。