Abstract

Three new highly modified lanostane triterpenoids schisanchinlactone A-C (1–3), together with six known compounds (4–9) were isolated from the stems and leaves of Schisandra chinensis. Their structures were established by extensive spectroscopic analyses. Compounds 7 and 8 showed significant inhibition of Cdc25A phosphatase with inhibitory rates of 85.5% and 98.1%, respectively, at the concentration of 100 μM.

中文翻译：

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五味子三萜类和木脂素及其对Cdc25A/B磷酸酶的抑制作用

摘要

从五味子的茎和叶中分离出三种新的高度改性羊毛甾烷三萜类五味子内酯 AC ( 1-3 ) ，以及六种已知化合物 ( 4-9 )。它们的结构是通过广泛的光谱分析确定的。化合物7和8在 100 μM 浓度下对 Cdc25A 磷酸酶有显着抑制作用，抑制率分别为 85.5% 和 98.1%。