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IgM, IgA and IgG response to conjugate polysaccharides in children with recurrent respiratory infections.
Scandinavian Journal of Immunology ( IF 4.1 ) Pub Date : 2020-08-07 , DOI: 10.1111/sji.12955
Filomena Monica Cavaliere 1 , Simona Graziani 2 , Elisabetta Del Duca 2 , Caterina Bilotta 1 , Mayla Sgrulletti 2 , Isabella Quinti 1 , Viviana Moschese 2
Affiliation  

Recurrent respiratory tract infections (rRTI) in children represent a challenge in physician’s practice and raise the suspicion of an immunological defect, when allergy and other chronic respiratory diseases are excluded [1]. When major primary antibody deficiencies are excluded [2‐4], the diagnosis of Unclassified Primary Antibody Deficiency (UnPAD) or a Specific Antibody Deficiency (SAD) due to a reduced response to purified or conjugate pneumococcal polysaccharide vaccine (PPV‐SAD and PCV‐SAD, respectively) should be considered [5].

中文翻译:

IgM,IgA和IgG对反复呼吸道感染儿童的共轭多糖反应。

儿童的反复呼吸道感染(rRTI)在排除过敏和其他慢性呼吸道疾病[1]时是医师实践的一个挑战,并增加了人们对免疫缺陷的怀疑。当排除主要的主要抗体缺陷时[2-4],由于对纯化或结合的肺炎球菌多糖疫苗(PPV-SAD和PCV-)的反应减少,因此诊断为未分类的主要抗体缺乏症(UnPAD)或特定抗体缺乏症(SAD)。 SAD)分别应考虑[5]。
更新日期:2020-08-08
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