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Optimization of compound-specific chlorine stable isotope analysis of chloroform using Taguchi design of experiments.
Rapid Communications in Mass Spectrometry ( IF 1.8 ) Pub Date : 2020-08-07 , DOI: 10.1002/rcm.8922
Berhane Abrha Asfaw 1 , Kaori Sakaguchi-Söder 1, 2 , Anat Bernstein 3 , Hagar Siebner 3 , Christoph Schüth 1
Affiliation  

Chloroform, a probable human carcinogen, is commonly detected in various concentration levels in many surface water and groundwater sources. Compound‐specific chlorine stable isotope analysis (Cl‐CSIA) is significant in investigating the fate of chlorinated contaminants in the environment. Analytical conditions should, however, be thoroughly examined for any isotopic fractionation. In this study, we simultaneously optimize three analytical parameters for a robust online Cl‐CSIA of chloroform using the Taguchi design of experiments.

中文翻译:

Taguchi设计的实验优化了氯仿的化合物特异性氯稳定同位素分析。

在许多地表水和地下水源中,通常以各种浓度水平检测到氯仿,可能是人类致癌物。化合物特定的氯稳定同位素分析(Cl-CSIA)对于研究环境中氯化污染物的结局具有重要意义。但是,应彻底检查分析条件是否有任何同位素分馏。在这项研究中,我们使用Taguchi设计的实验,同时针对稳定的在线氯仿Cl-CSIA优化了三个分析参数。
更新日期:2020-09-16
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