We are grateful to Dr Finsterer and colleagues for the important points raised on our study which also highlight more general issues in conducting neuropathological research in SUDEP. The SUDEP cases were mainly community deaths in domestic settings, with post-mortem investigations falling under the jurisdiction of the Coroner and local pathology services. In the UK, the Royal college of Pathologists has provided guidance for the methodological approaches to these post-mortem examinations since 2006, recommending referral of brain and heart for examination to specialist centres or mandatory minimum histology of organs.

中文翻译：

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为了应对“脑干网状区的容量减少和神经元组成的改变可能不会导致癫痫患者突然意外死亡”

我们感谢 Finsterer 博士及其同事在我们的研究中提出的重要观点，这些观点也突出了在 SUDEP 中进行神经病理学研究中更普遍的问题。SUDEP 案件主要是家庭环境中的社区死亡，验尸调查属于死因裁判官和当地病理服务机构的管辖范围。在英国，自 2006 年以来，皇家病理学家学院为这些尸检的方法学方法提供了指导，建议将大脑和心脏转诊到专科中心或强制性最低限度的器官组织学检查。