Abstract

Calcium phosphate ceramics in the Ca₂P₂O₇–Ca(PO₃)₂ system was obtained by annealing of hardened samples formed from highly loaded suspensions (HLS). HLSs included water and a homogenized powder mixture of calcium citrate tetrahydrate Ca₃(C₆H₅O₇)₂ ⋅ 4H₂O and monocalcium phosphate monohydrate Ca(H₂PO₄)₂ ⋅ H₂O. The latter was taken in the amount providing the molar ratio of Ca/P = 1 in the powder mixture, as well as at a molar ratio of Ca/P < 1 so that the excess of monocalcium phosphate monohydrate Ca(H₂PO₄)₂ ⋅ H₂O provided the formation of the calcium polyphosphate Ca(PO₃)₂ phase upon annealing. The samples were molded by extrusion of the HLS through a die with a diameter of 2 mm by sandwiching powder cords. After hardening and drying, the phase composition of all obtained samples included brushite CaHPO₄ ⋅ 2H₂O, monetite CaHPO₄, monocalcium phosphate monohydrate Ca(H₂PO₄)₂ · H₂O, and octacalcium phosphate Ca₈(HPO₄)₂(PO₄)₄H₂O. According to the XRD data, the phase composition of all ceramic samples after annealing in a range of 800–1000°C included calcium β-pyrophosphate β-Ca₂P₂O₇, and a ceramic sample obtained from a powder mixture with the highest excess of monocalcium phosphate monohydrate Ca(H₂PO₄)₂ · H₂O additionally included tromelite Ca₄P₆O₁₉. Hardening HLSs containing water and a homogenized powder mixture of calcium citrate Ca₃(C₆H₅O₇)₂ · 4H₂O and monocalcium phosphate monohydrate Ca(H₂PO₄)₂ · H₂O can be used for layer-by-layer extrusion molding. The resulting calcium phosphate ceramics with lowered sintering temperature can be used for the design of a resorbable matrices of tissue engineering constructs.

中文翻译：

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Ca 2 P 2 O 7 -Ca（PO 3）2体系中的陶瓷通过对基于柠檬酸钙四水合物和一水合一磷酸钙的硬化混合物制成的样品进行退火而获得

摘要

Ca ₂ P ₂ O ₇ -Ca（PO ₃）₂系统中的磷酸钙陶瓷是通过对由高负载悬浮液（HLS）形成的硬化样品进行退火而获得的。HLSs包括水和柠檬酸钙四水合物的粉末均化混合物的Ca ₃（C ₆ H ^ ₅ ö ₇）₂ ⋅4H ₂ O和磷酸一钙一水合物的Ca（H ₂ PO ₄）₂ ⋅ħ ₂O.后者的用量应使粉末混合物中Ca / P的摩尔比为1，并且Ca / P <1的摩尔比使过量的磷酸一钙一水合物Ca（H ₂ PO ₄）₂ ⋅ħ ₂ ö提供的聚磷酸钙Ca的形成（PO ₃）₂在退火阶段。通过将HLS挤出通过夹有粉末帘线的直径为2 mm的模具来成型。硬化和干燥后，所有获得的样品的相组成包含透钙磷石使用CaHPO ₄ ⋅2H ₂ O，斜磷钙石使用CaHPO ₄，磷酸二氢钙一水合物的Ca（H ₂ PO₄）₂ ·H ₂ O，和磷酸八钙的Ca ₈（HPO ₄）₂（PO ₄）₄ ħ ₂ O.根据XRD数据，在一个范围内的退火800-1000毕竟陶瓷样品的相组成° ç包括钙β-焦β钙₂ P ₂ ö ₇，并从具有最高过量磷酸二氢钙一水合物的Ca（H的粉末混合物而得到的陶瓷样品₂ PO ₄）₂ ·H ₂ ö另外包括tromelite的Ca ₄ P ₆ Ø₁₉。包含水和柠檬酸钙Ca ₃（C ₆ H ₅ O ₇）₂ ·4H ₂ O和一水合磷酸一钙Ca（H ₂ PO ₄）₂ ·H ₂ O的均质粉末混合物的硬化HLS可以分层使用层挤出成型。所得的具有降低的烧结温度的磷酸钙陶瓷可用于组织工程构造的可吸收基质的设计。