There is no consensus on the best choice between high- and low-viscosity bone cement for percutaneous vertebroplasty (PVP). This study aimed to compare the clinical and radiological outcomes and leakage between three cements with different viscosities in treating osteoporotic vertebral compression fractures. This is a prospective study comparing patients who were treated with PVP under local anesthesia: group A (n = 99, 107 vertebrae) with high-viscosity OSTEOPAL V cement, group B (n = 79, 100 vertebrae) with low-viscosity OSTEOPAL V cement, and group C (n = 88, 102 vertebrae) with low-viscosity Eurofix VTP cement. Postoperative pain severity was evaluated using the visual analog scale. Cement leakage was evaluated using radiography and computed tomography. There was no significant difference in the incidence of cement leakage between the three groups (group A 20.6%, group B 24.2%, group C 20.6%, P = 0.767). All three groups showed significant reduction in postoperative pain scores but did not differ significantly in pain scores at postoperative 2 days (group A 2.01 ± 0.62, group B 2.15 ± 0.33, group C 1.92 ± 0.71, P = 0.646). During the 6 months after cement implantation, significantly less reduction in the fractured vertebral body height was noticed in group B and group C than in group A (group A 19.0%, group B 8.1%, group C 7.3%, P = 0.009). Low-viscosity cement has comparable incidence of leakage compared to high-viscosity cement in PVP for osteoporotic vertebral compression fractures. It also can better prevent postoperative loss of fractured vertebral body’s height.

中文翻译：

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经皮椎体成形术使用高粘度和低粘度骨水泥治疗骨质疏松性椎体压缩性骨折。

对于高粘度和低粘度骨水泥经皮椎体成形术（PVP）的最佳选择尚无共识。本研究旨在比较三种粘度不同的骨水泥治疗骨质疏松性椎体压缩性骨折的临床和影像学结果以及渗漏情况。这项前瞻性研究比较了在局部麻醉下接受PVP治疗的患者：A组（n = 99，107椎骨）与高粘度OSTEOPAL V水泥，B组（n = 79，100椎骨）与低粘度OSTEOPAL V水泥，以及C组（n = 88、102椎骨）和低粘度Eurofix VTP水泥。使用视觉模拟量表评估术后疼痛的严重程度。使用射线照相和计算机断层扫描技术评估水泥渗漏情况。三组之间的水泥渗漏发生率无显着差异（A组为20.6％，B组为24.2％，C组为20.6％，P = 0.767）。这三组患者的术后疼痛评分均显着降低，但术后2天的疼痛评分没有显着差异（A组2.01±0.62，B组2.15±0.33，C组1.92±0.71，P = 0.646）。在骨水泥植入后的6个月内，B组和C组的骨折椎体高度明显低于A组（A组19.0％，B组8.1％，C组7.3％，P = 0.009）。对于骨质疏松性椎体压缩性骨折，PVP中低粘度水泥的渗漏发生率可与高粘度水泥相比。它还可以更好地防止术后椎体高度的丢失。B组24.2％，C组20.6％，P = 0.767）。这三组患者的术后疼痛评分均显着降低，但术后2天的疼痛评分没有显着差异（A组2.01±0.62，B组2.15±0.33，C组1.92±0.71，P = 0.646）。在骨水泥植入后的6个月内，B组和C组的骨折椎体高度降低明显少于A组（A组19.0％，B组8.1％，C组7.3％，P = 0.009）。在骨质疏松性椎体压缩性骨折中，与PVP中的高粘度水泥相比，低粘度水泥的渗漏发生率相当。它还可以更好地防止术后椎体高度的丢失。B组24.2％，C组20.6％，P = 0.767）。这三组患者的术后疼痛评分均显着降低，但术后2天的疼痛评分没有显着差异（A组2.01±0.62，B组2.15±0.33，C组1.92±0.71，P = 0.646）。在骨水泥植入后的6个月内，B组和C组的骨折椎体高度明显低于A组（A组19.0％，B组8.1％，C组7.3％，P = 0.009）。在骨质疏松性椎体压缩性骨折中，与PVP中的高粘度水泥相比，低粘度水泥的渗漏发生率相当。它还可以更好地防止术后椎体高度的丢失。这三组患者的术后疼痛评分均显着降低，但术后2天的疼痛评分没有显着差异（A组2.01±0.62，B组2.15±0.33，C组1.92±0.71，P = 0.646）。在骨水泥植入后的6个月内，B组和C组的骨折椎体高度明显低于A组（A组19.0％，B组8.1％，C组7.3％，P = 0.009）。对于骨质疏松性椎体压缩性骨折，PVP中低粘度水泥的渗漏发生率与高粘度水泥相当。它还可以更好地防止术后椎体高度的丢失。这三组患者的术后疼痛评分均显着降低，但术后2天的疼痛评分没有显着差异（A组2.01±0.62，B组2.15±0.33，C组1.92±0.71，P = 0.646）。在骨水泥植入后的6个月内，B组和C组的骨折椎体高度降低明显少于A组（A组19.0％，B组8.1％，C组7.3％，P = 0.009）。在骨质疏松性椎体压缩性骨折中，与PVP中的高粘度水泥相比，低粘度水泥的渗漏发生率相当。它还可以更好地防止术后椎体高度的丢失。与A组相比，B组和C组的椎体骨折高度明显减少（A组19.0％，B组8.1％，C组7.3％，P = 0.009）。在骨质疏松性椎体压缩性骨折中，与PVP中的高粘度水泥相比，低粘度水泥的渗漏发生率相当。它还可以更好地防止术后椎体高度的丢失。与A组相比，B组和C组的椎体骨折高度明显减少（A组19.0％，B组8.1％，C组7.3％，P = 0.009）。在骨质疏松性椎体压缩性骨折中，与PVP中的高粘度水泥相比，低粘度水泥的渗漏发生率相当。它还可以更好地防止术后椎体高度的丢失。