当前位置: X-MOL 学术Org. Lett. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Pd/Cu-Catalyzed Domino Cyclization/Deborylation of Alkene-Tethered Carbamoyl Chloride and 1,1-Diborylmethane.
Organic Letters ( IF 4.9 ) Pub Date : 2020-08-05 , DOI: 10.1021/acs.orglett.0c02211
Chenhuan Zhang 1 , Xianqing Wu 1 , Chenchen Wang 1 , Chengxi Zhang 1 , Jingping Qu 1 , Yifeng Chen 1
Affiliation  

Reported herein is a palladium/copper cooperative-catalyzed dicarbofunctionalization of alkene-tethered carbamoyl chlorides with 1,1-diborylmethane. This cyclization/deborylation cascade strategy allows for the expedient formation of the versatile borylated 3,3-disubstituted oxindole skeleton, allowing for further functionalization via the derivatization of the carbon–boron bond.

中文翻译:

Pd / Cu催化的烯烃系氨基甲酰氯和1,1-二硼烷基甲烷的多米诺环化/脱硼化反应。

本文报道的是链烯键合的氨基甲酰氯与1,1-二硼烷基甲烷的钯/铜协同催化双碳官能化。这种环化/去硼化的级联策略可以方便地形成通用的3,3-二取代的羟吲哚骨架,并可以通过碳-硼键的衍生化进一步功能化。
更新日期:2020-08-21
down
wechat
bug