Abstract

The reaction between [MoO₂(acac)₂] and an ONO type Schiff-base ligand (L=(E)-4-bromo-2-(((2-hydroxyphenyl)imino)methyl)phenol) resulted a new oligomer molybdenum complex ([MoO₂(L)]_n). The oligomer complex was characterized by elemental analysis and FT-IR. The promotion ability of the compound on the osteoblast was measured with Cell Counting Kit-8 assay. The ELISA detection was performed to detect the TNF-α content released by the osteoblast. The activity of the complex to the protein is estimated and investigated by performing the molecular docking simulation.

中文翻译：

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钼席夫碱复合物：通过减少TNF-α的释放来修复与正畸相关的根吸收的活性

抽象的

[MoO ₂（acac）₂ ]与ONO型席夫碱配体（L =（E）-4-bromo-2-（（（（2-羟苯基）亚氨基）甲基）苯酚）之间的反应产生了一种新的低聚物钼（[MoO ₂（L）] _n）。通过元素分析和FT-IR对低聚物配合物进行表征。用Cell Counting Kit-8测定法测定化合物对成骨细胞的促进能力。进行ELISA检测以检测成骨细胞释放的TNF-α含量。通过进行分子对接模拟，估计并研究了复合物对蛋白质的活性。