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Precise diagnosis of Neisseria macacae infective endocarditis assisted by nanopore sequencing.
Emerging Microbes & Infections ( IF 13.2 ) Pub Date : 2020-08-24 , DOI: 10.1080/22221751.2020.1807411
Jing-Wen Ai 1 , Hong Liu 2 , Hui-Xia Li 1, 3 , Qing-Xia Ling 1, 4 , Yan-Qin Ai 1, 5 , Si-Jia Sun 1, 6 , Xuan Wang 1 , Bing-Yan Zhang 1 , Jian-Ming Zheng 1 , Jia-Lin Jin 1 , Wen-Hong Zhang 1
Affiliation  

Infective endocarditis caused by Neisseria macacae in humans is extremely rare. We presented here a case of N. macacae infective endocarditis in a 61-year-old man with a native aortic valve infection. N. macacae was isolated from blood culture and was detected by nanopore-based metagenomic sequencing in the vegetations. Finally, the patient recovered completely after surgery and antibiotic therapy.



中文翻译:

纳米孔测序辅助精确诊断猕猴感染性心内膜炎。

在人类中,由猕猴杆菌引起的感染性心内膜炎极为罕见。我们在这里介绍了一名患有自然主动脉瓣感染的61岁男子的猕猴感染性心内膜炎的病例。从血培养物中分离出猕猴,并通过基于纳米孔的宏基因组测序在植被中检测到。最终,患者在接受手术和抗生素治疗后完全康复。

更新日期:2020-08-25
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