Summary The effect of probiotic strains (Enterococcus faecium EF55, E. faecium CCM7420, E. faecium CCM8558, E. durans ED26E/7, Lactobacillus fermentum CCM7421, L. plantarum 17L/1) on the production of superoxide anion (O2-) in peritoneal macrophages of Trichinella spiralis infected mice was examined. E. faecium EF55 and E. faecium CCM8558 strains increased the O2-production prior to parasitic infection,at the day7of application.A significant inhibition of the O2- production caused by T. spiralis infection on day 5 post infection (p.i.) was prevented by all examined strains. Lactobacilli stimulated metabolic activity of macrophages during intestinal and early muscular phase (from day 5 to 25 p.i.) of trichinellosis. Enterococci increased the O2- production in early intestinal phase (day 5 p.i.) and during the muscular phase of trichinellosis (days 25 and 32 p.i.). Respected increase in macrophage’s metabolic activity induced by probiotic treatment in the intestinal phase of trichinellosis augmented the host antiparasite defence (damage and killing of newborn larvae with reactive oxygen species from macrophages).

中文翻译：

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益生菌可以调节旋毛虫感染中鼠巨噬细胞的超氧化物产生

总结 益生菌菌株（屎肠球菌 EF55、屎肠球菌 CCM7420、屎肠球菌 CCM8558、杜兰肠杆菌 ED26E/7、发酵乳杆菌 CCM7421、植物乳杆菌 17L/1）对超氧阴离子 (O2-) 产生的影响检查了旋毛虫感染小鼠的腹膜巨噬细胞。E. faecium EF55 和 E. faecium CCM8558 菌株在寄生虫感染前，在施用的第 7 天增加了 O2-生产。在感染后第 5 天 (pi) 防止了由 T.spiralis 感染引起的 O2-生产的显着抑制所有检查的菌株。乳酸杆菌在旋毛虫病的肠道和早期肌肉阶段（从第 5 天到第 25 天）刺激巨噬细胞的代谢活动。肠球菌在肠道早期阶段（感染后第 5 天）增加了 O2- ) 和在旋毛虫病的肌肉阶段（第 25 天和第 32 天）。在旋毛虫病的肠道阶段，益生菌治疗引起巨噬细胞代谢活性的显着增加增强了宿主抗寄生虫防御（用巨噬细胞的活性氧对新生幼虫的伤害和杀死）。