Adult neurogenesis—resulting in adult-generated functioning, integrated neurons—is still one of the most captivating research areas of neuroplasticity. The addition of new neurons in adulthood follows a seemingly consistent multi-step process. These neurogenic stages include proliferation, differentiation, migration, maturation/survival, and integration of new neurons into the existing neuronal network. Most studies assessing the impact of exogenous (e.g., restraint stress) or endogenous (e.g., neurotrophins) factors on adult neurogenesis have focused on proliferation, survival, and neuronal differentiation. This review will discuss the multifaceted impact of hormones on these various stages of adult neurogenesis. Specifically, we will review the evidence for hormonal facilitation (via gonadal hormones), inhibition (via glucocorticoids), and neuroprotection (via recruitment of other neurochemicals such as neurotrophin and neuromodulators) on newly adult-generated neurons in the mammalian brain.

中文翻译：

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哺乳动物成年神经发生的激素调节：一个多方面的机制。

成人神经发生——导致成人生成的功能性整合神经元——仍然是神经可塑性最引人入胜的研究领域之一。成年后新神经元的添加遵循看似一致的多步骤过程。这些神经源性阶段包括增殖、分化、迁移、成熟/存活以及新神经元整合到现有神经元网络中。大多数评估外源性（例如约束压力）或内源性（例如神经营养因子）因素对成人神经发生的影响的研究都集中在增殖、存活和神经元分化上。这篇综述将讨论激素对成人神经发生的这些不同阶段的多方面影响。具体来说，我们将审查激素促进（通过性腺激素）、抑制（通过糖皮质激素）、