Membrane trafficking is critical for cell compartmentation which allows the maintenance of specialised environments required for specific cellular activities. To achieve this goal, cells need to tightly regulate vesicle transport between donor and acceptor compartments. Several different protein families are involved: among them the SNAREs (65 genes) and the small GTPases Rabs (57 genes) show the highest number of isoforms and will be in the spotlight. We will focus on the roles of these proteins in the ER–Golgi–plasma membrane pathway to illustrate how Rabs and SNAREs are involved to achieve specific set of functions.

中文翻译：

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rabs 和 snares 在分泌途径和植物发育中的复杂作用：一个永无止境的故事……

膜运输对于细胞区室至关重要，细胞区室允许维护特定细胞活动所需的专门环境。为了实现这一目标，细胞需要严格调节供体和受体隔室之间的囊泡运输。涉及几个不同的蛋白质家族：其中 SNARE（65 个基因）和小 GTPases Rab（57 个基因）显示出最多的同种型并将成为焦点。我们将关注这些蛋白质在内质网-高尔基体-质膜通路中的作用，以说明 Rab 和 SNARE 如何参与实现特定的功能集。