An oral mass was surgically excised from the gingiva of a pig. As the mass had a similar histological appearance to an equine sarcoid, DNA was extracted and consensus PCR primers used to amplify papillomavirus (PV) DNA. DNA sequences from Ovis aries papillomavirus (OaPV) type 2 were amplified both from a section of the entire mass as well as an area deeper within the mass away from the surface of the lesion. No other PV types were detected within the oral lesion. Ovis aries PV2 is a Delta PV that is closely related to the bovine Delta PVs that cause sarcoids in horses and cats. These results suggest that OaPV2 may be able to infect pigs and this virus could have caused the mesenchymal neoplasm in the mouth of this pig. This is the first evidence that a non-bovine PV can infect a non-host species and the first report of a sarcoid-like mass in pigs. These observations add to the range of species in which PV-associated neoplasia has been reported and suggest that cross-species infection by other Delta PV types may be possible.

从猪的牙龈手术切除口腔块。由于该肿块具有类似于马肉瘤的组织学外观，因此提取了DNA，并使用共有PCR引物扩增乳头瘤病毒（PV）DNA。从整个肿块的一部分以及肿块内远离病灶表面的较深区域都扩增了来自2型Ovis aries乳头瘤病毒（OaPV）的DNA序列。口腔病变内未检测到其他PV类型。Ovisaries PV2是与牛三角洲密切相关的三角洲PV在马和猫中引起结节病的PV。这些结果表明，OaPV2可能能够感染猪，并且这种病毒可能已经引起了该猪口中的间质瘤。这是非牛PV可以感染非宿主物种的第一个证据，也是猪类肉瘤样块的首次报道。这些观察结果增加了报道PV相关肿瘤的物种范围，并表明其他三角洲PV类型的跨物种感染也是可能的。