Highly efficient access to both enantiomers of chiral molecules is a long-standing challenge in synthetic chemistry. In a recent paper published in Nature Chemistry, Shu-Li You and coworkers reported a time-dependent enantiodivergent synthesis of chiral amines through an iridium-catalyzed allylic substitution reaction involving two kinetic resolutions.

中文翻译：

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允许时间依赖的对映异构合成的非常规催化剂

高效获得手性分子的两个对映异构体是合成化学领域的长期挑战。在《自然化学》上发表的最新论文中，尤树立及其同事报道了铱催化的烯丙基取代反应（涉及两个动力学拆分）的时间依赖性对映体手性胺的合成。