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Choroid Plexus Organoids: Harnessing CSF Gatekeepers for Brain Therapeutics.
Cell Stem Cell ( IF 19.8 ) Pub Date : 2020-08-06 , DOI: 10.1016/j.stem.2020.07.009
Huixin Xu 1 , Maria K Lehtinen 1
Affiliation  

Barrier properties of the choroid plexus (ChP) help protect the brain from the external world. In Science, Pellegrini et al. (2020) report the successful creation of human ChP organoids, which produce a cerebrospinal fluid-like secretion and recapitulate barrier functions, thereby inspiring new advances for targeted brain therapeutics.



中文翻译:

脉络丛神经器官:利用CSF看门人进行脑部治疗。

脉络丛(ChP)的屏障特性有助于保护大脑免受外界干扰。在《科学》杂志中,Pellegrini等人。(2020)报告成功创建了人类ChP类器官,该类器官产生脑脊液样分泌并重现了屏障功能,从而激发了针对性脑治疗的新进展。

更新日期:2020-08-06
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