Oguri and colleagues use single-cell RNA sequencing to identify a beige adipocyte precursor cell that gives rise to thermogenic adipocytes in subcutaneous adipose tissue. These beige fat progenitors are marked by PDGFRα, Sca1, and CD81 and proliferate upon activation of FAK-signaling in response to the cold and irisin.

中文翻译：

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大海捞针：米色脂肪祖细胞的鉴定。

Oguri 及其同事使用单细胞 RNA 测序来鉴定一种米色脂肪细胞前体细胞，该细胞在皮下脂肪组织中产生产热脂肪细胞。这些米色脂肪祖细胞以 PDGFRα、Sca1 和 CD81 为标志，并在响应寒冷和鸢尾素的 FAK 信号激活后增殖。